New research reveals that patients who come off new slimming jabs like Mounjaro or Wegovy may regain lost weight at a significantly accelerated pace than those who halt traditional diet and exercise programs.
Published data in a major medical journal points out that while overweight individuals can lose about a fifth of their body weight while using the jabs, the weight comes back at an estimated rate of 0.8 kg per month once they quit.
"People purchasing these treatments must be aware of the potential of fast weight regain when the medication ends," stated researcher Dr. Susan Jebb.
That rate of recovery means a reversion to pre-treatment mass in about 18 months.
Analyzing Treatments
The research, which reviewed dozens of studies involving over 9,000 of patients, compared the effects of GLP-1 agonists with other pills.
Researchers note that individuals who shed pounds through dieting usually have a more gradual creep back—around 0.1 kg a month—once they finish.
Explaining the Fast Regain
Nutrition scientists propose the mode of action of the jabs accounts for the accelerated regain.
These medications mimic a natural hormone called GLP-1, which moderates feelings of fullness.
"Long-term administration of the hormone levels several times higher than normal might result in the system to produce less of its own natural hormone, and may also diminish sensitivity to its effects," said Dr. Adam Collins, a nutrition specialist.
"Stopping of this GLP-1 'fix' results in appetite is uncontrolled, making overeating a significant risk."
An Ongoing Condition?
Health authorities recommend the injections for people with obesity-related health risks, accompanied by recommended lifestyle changes.
Professionals argue that, given the high risk of relapse, the treatment should be considered ongoing.
This opinion is supported by drug manufacturers, who note that the findings "underscore the chronic nature of excess weight," comparing it to managing conditions like diabetes.
User Accounts
Users who have stopped the medication explain a powerful return of cravings.
"It felt as if something that goes on and I was suddenly starving," said an individual.
This difficulty is compounded if users have not developed permanent lifestyle or habit changes during treatment.
Significant Adoption
Figures show that a significant number of people in the UK have tried weight-loss jabs in the last 12 months, with interest being substantial.
- Use is higher among women than males.
- The middle-aged age group shows the highest level of interest.
- Many obtain the drugs through private healthcare rather than public health services.
In conclusion, experts caution that while these medications are potent agents for weight loss, they are not a permanent solution and maintained weight loss hinges on combined behavioural support.
